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Design of 5-fluorouracil (5-FU) loaded, folate conjugated peptide linked nanoparticles, a potential new drug carrier for selective targeting of tumor cells

In the present investigation folate peptide (FA-Pep) conjugated 5-fluorouracil (5-FU) loaded nanoparticles were synthesized and their tumor targeting potentiality was monitored by different in vitro and in vivo techniques. FA-Pep-1 and FA-Pep-2 were synthesized and radiolabeled with (99m)Tc(CO)(3)(H...

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Publicat a:Medchemcomm
Autors principals: Kazi, Julekha, Mukhopadhyay, Ria, Sen, Ramkrishna, Jha, Tarun, Ganguly, Shantanu, Debnath, Mita Chatterjee
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482664/
https://ncbi.nlm.nih.gov/pubmed/31057736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00565f
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