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Enhanced brain targeting efficiency using 5-FU (fluorouracil) lipid–drug conjugated nanoparticles in brain cancer therapy

The present investigation was aimed to synthesize, optimize, and characterize lipid/drug conjugate nanoparticles for delivering 5-fluorouracil (5-FU) to treat brain cancer. The Box–Behnken design was used to optimize the formulation, evaluate the particle size, entrapment efficiency, morphology, in...

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Detalhes bibliográficos
Publicado no:Prog Biomater
Main Authors: Shinde, Gajanan, Shiyani, Sangita, Shelke, Santosh, Chouthe, Rashmi, Kulkarni, Deepak, Marvaniya, Khushboo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718375/
https://ncbi.nlm.nih.gov/pubmed/33252721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40204-020-00147-y
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