Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells

The alpha subunit of the voltage gated human ether-a-go-go-related (hERG) potassium channel regulates cell excitability in a broad range of cell lines. HERG channels are also expressed in a variety of cancer cells and control cell proliferation and apoptosis. Hypoxia, a common feature of tumors, alt...

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Udgivet i:PLoS One
Main Authors: Vaddi, Damodara Reddy, Piao, Lin, Khan, Shakil A., Wang, Ning, Prabhakar, Nanduri R., Nanduri, Jayasri
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481834/
https://ncbi.nlm.nih.gov/pubmed/31017964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215905
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