Targeting claudin-4 enhances CDDP-chemosensitivity in gastric cancer

Claudins are major tight-junction proteins that mediate cellular polarity and differentiation. The present study investigated whether the 4D3 antibody to the human CLDN4 extracellular domain (that we previously established) is capable of modulating chemotherapeutic sensitivity in gastric cancer (GC)...

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Vydáno v:Oncotarget
Hlavní autoři: Nishiguchi, Yukiko, Fujiwara-Tani, Rina, Sasaki, Takamitsu, Luo, Yi, Ohmori, Hitoshi, Kishi, Shingo, Mori, Shiori, Goto, Kei, Yasui, Wataru, Sho, Masayuki, Kuniyasu, Hiroki
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481338/
https://ncbi.nlm.nih.gov/pubmed/31040910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26758
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