Anti-claudin-4 extracellular domain antibody enhances the antitumoral effects of chemotherapeutic and antibody drugs in colorectal cancer

Claudin-4 (CLDN4) is a major epithelial tight junction protein overexpressed in many cancers to maintain the tumor environment. In this report, we aimed to determine the efficacy of targeting CLDN4 in colorectal cancer (CRC) using an anti-CLDN4 extracellular domain antibody, 4D3. CLDN4 was upregulat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fujiwara-Tani, Rina, Sasaki, Takamitsu, Luo, Yi, Goto, Kei, Kawahara, Isao, Nishiguchi, Yukiko, Kishi, Shingo, Mori, Shiori, Ohmori, Hitoshi, Kondoh, Masuo, Kuniyasu, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324772/
https://ncbi.nlm.nih.gov/pubmed/30647838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26427
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados