Anti-claudin-4 extracellular domain antibody enhances the antitumoral effects of chemotherapeutic and antibody drugs in colorectal cancer

Claudin-4 (CLDN4) is a major epithelial tight junction protein overexpressed in many cancers to maintain the tumor environment. In this report, we aimed to determine the efficacy of targeting CLDN4 in colorectal cancer (CRC) using an anti-CLDN4 extracellular domain antibody, 4D3. CLDN4 was upregulat...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Fujiwara-Tani, Rina, Sasaki, Takamitsu, Luo, Yi, Goto, Kei, Kawahara, Isao, Nishiguchi, Yukiko, Kishi, Shingo, Mori, Shiori, Ohmori, Hitoshi, Kondoh, Masuo, Kuniyasu, Hiroki
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324772/
https://ncbi.nlm.nih.gov/pubmed/30647838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26427
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars