Targeting claudin‐4 enhances chemosensitivity of pancreatic ductal carcinomas

Claudin (CLDN) family comprises of protein that form a tight junction, and is involved in regulating polarity and differentiation of cells. Here, we aimed to investigate the effects of inhibiting CLDN4 in pancreatic ductal carcinomas (PDC). We first examined 91 cases of human PDC by immunohistochemi...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Sasaki, Takamitsu, Fujiwara‐Tani, Rina, Kishi, Shingo, Mori, Shiori, Luo, Yi, Ohmori, Hitoshi, Kawahara, Isao, Goto, Kei, Nishiguchi, Yukiko, Mori, Takuya, Sho, Masayuki, Kondo, Masuo, Kuniyasu, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825989/
https://ncbi.nlm.nih.gov/pubmed/31498559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2547
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