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Improved Detection and Fragmentation of Disulphide-Linked Peptides

Characterisation of peptides containing intact disulphide bonds (DSBs) via mass spectrometry is challenging. Our study demonstrates that the addition of aniline to alpha-cyano-4-hydroxycinnamic acid improves detection and fragmentation of complex DSB peptides by matrix-assisted laser desorption/ioni...

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Detalhes bibliográficos
Publicado no:Methods Protoc
Main Authors: Maes, Evelyne, Clerens, Stefan, Dyer, Jolon M., Deb-Choudhury, Santanu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481087/
https://ncbi.nlm.nih.gov/pubmed/31164574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/mps1030033
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