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Incorporating individual historical controls and aggregate treatment effect estimates into a Bayesian survival trial: a simulation study
BACKGROUND: Performing well-powered randomised controlled trials (RCTs) of new treatments for rare diseases is often infeasible. However, with the increasing availability of historical data, incorporating existing information into trials with small sample sizes is appealing in order to increase the...
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| Publicado no: | BMC Med Res Methodol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6480797/ https://ncbi.nlm.nih.gov/pubmed/31018832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-019-0714-z |
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