Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers

An ever-growing number of preclinical studies have investigated the tumoricidal activity of the milk thistle flavonolignan silibinin. The clinical value of silibinin as a bona fide anti-cancer therapy, however, remains uncertain with respect to its bioavailability and blood–brain barrier (BBB) perme...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Pérez-Sánchez, Almudena, Cuyàs, Elisabet, Ruiz-Torres, Verónica, Agulló-Chazarra, Luz, Verdura, Sara, González-Álvarez, Isabel, Bermejo, Marival, Joven, Jorge, Micol, Vicente, Bosch-Barrera, Joaquim, Menendez, Javier A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480586/
https://ncbi.nlm.nih.gov/pubmed/30935093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071606
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