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Hydrogen-Deuterium Exchange Mass Spectrometry of Membrane Proteins in Lipid Nanodiscs

Hydrogen deuterium exchange mass spectrometry (H/DX MS) provides a quantitative comparison of the relative rates of exchange of amide protons for solvent deuterons. In turn, the rate of amide exchange depends on a complex combination of the stability of local secondary structure, solvent accessibili...

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Bibliographic Details
Published in:Chem Phys Lipids
Main Authors: Redhair, Michelle, Clouser, Amanda F., Atkins, William M.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480397/
https://ncbi.nlm.nih.gov/pubmed/30802434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2019.02.007
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