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Mitochondrial Targeting of Antioxidants Alters Pancreatic Acinar Cell Bioenergetics and Determines Cell Fate

Mitochondrial dysfunction is a core feature of acute pancreatitis, a severe disease in which oxidative stress is elevated. Mitochondrial targeting of antioxidants is a potential therapeutic strategy for this and other diseases, although thus far mixed results have been reported. We investigated the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Armstrong, Jane A., Cash, Nicole J., Morton, Jack C., Tepikin, Alexei V., Sutton, Robert, Criddle, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480340/
https://ncbi.nlm.nih.gov/pubmed/30959771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071700
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