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Efficient transduction of human hematopoietic repopulating cells with a chimeric HIV1-based vector including SIV capsid
Innate immune factors, such as TRIM5α and cyclophilin A (CypA), act as a major restriction factor of retroviral infection among species. When HIV1 infects human cells, HIV1 capsid binds to human CypA to escape from human TRIM5α restriction. However, in rhesus cells, the mismatch between HIV1 capsid...
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| Publicado no: | Exp Hematol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6480307/ https://ncbi.nlm.nih.gov/pubmed/23665451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2013.04.014 |
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