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Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress

Ring finger protein 146 (RNF146) is an E3 ubiquitin ligase whose activity prevents poly (ADP-ribose) polymerase 1 (PARP1)-dependent neurodegeneration in Parkinson’s disease (PD). Previously, we reported that rhododendrin is a chemical inducer that increases RNF146 expression. However, the molecular...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Hyojung, Park, Jisoo, Leem, HyunHee, Cho, MyoungLae, Yoon, Jin-Ha, Maeng, Han-Joo, Lee, Yunjong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479468/
https://ncbi.nlm.nih.gov/pubmed/30974833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071772
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