Empagliflozin Attenuates Myocardial Sodium and Calcium Dysregulation and Reverses Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats

Diabetes mellitus (DM) has significant effects on cardiac calcium (Ca(2+)) and sodium (Na(+)) regulation. Clinical studies have shown that empagliflozin (Jardiance™) has cardiovascular benefits, however the mechanisms have not been fully elucidated. This study aimed to investigate whether empagliflo...

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Publicat a:Int J Mol Sci
Autors principals: Lee, Ting-I, Chen, Yao-Chang, Lin, Yung-Kuo, Chung, Cheng-Chih, Lu, Yen-Yu, Kao, Yu-Hsun, Chen, Yi-Jen
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479313/
https://ncbi.nlm.nih.gov/pubmed/30987285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071680
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