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Redox and Activation of Protein Kinase A Dysregulates Calcium Homeostasis in Pulmonary Vein Cardiomyocytes of Chronic Kidney Disease

BACKGROUND: Chronic kidney disease (CKD) increases the occurrence of atrial fibrillation and pulmonary vein (PV) arrhythmogenesis. Calcium dysregulation and reactive oxygen species (ROS) enhance PV arrhythmogenic activity. The purposes of this study were to investigate whether CKD modulates PV elect...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Huang, Shih‐Yu, Chen, Yao‐Chang, Kao, Yu‐Hsun, Hsieh, Ming‐Hsiung, Lin, Yung‐Kuo, Chen, Shih‐Ann, Chen, Yi‐Jen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586294/
https://ncbi.nlm.nih.gov/pubmed/28701305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.005701
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