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Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes
Fibroblast growth factor 23 (FGF23), elevated in chronic renal failure, increases atrial arrhythmogenesis and dysregulates calcium homeostasis. Late sodium currents (I(Na-Late)) critically induces ectopic activity of pulmoanry vein (the most important atrial fibrillation trigger). This study was to...
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Publicado no: | Oncotarget |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342473/ https://ncbi.nlm.nih.gov/pubmed/27713141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12470 |
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