Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes

Fibroblast growth factor 23 (FGF23), elevated in chronic renal failure, increases atrial arrhythmogenesis and dysregulates calcium homeostasis. Late sodium currents (I(Na-Late)) critically induces ectopic activity of pulmoanry vein (the most important atrial fibrillation trigger). This study was to...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Huang, Shih-Yu, Chen, Yao-Chang, Kao, Yu-Hsun, Hsieh, Ming-Hsiung, Lin, Yung-Kuo, Chung, Cheng-Chih, Lee, Ting-I, Tsai, Wen-Chin, Chen, Shih-Ann, Chen, Yi-Jen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper: Pathology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342473/
https://ncbi.nlm.nih.gov/pubmed/27713141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12470
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