Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes

Fibroblast growth factor 23 (FGF23), elevated in chronic renal failure, increases atrial arrhythmogenesis and dysregulates calcium homeostasis. Late sodium currents (I(Na-Late)) critically induces ectopic activity of pulmoanry vein (the most important atrial fibrillation trigger). This study was to...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Huang, Shih-Yu, Chen, Yao-Chang, Kao, Yu-Hsun, Hsieh, Ming-Hsiung, Lin, Yung-Kuo, Chung, Cheng-Chih, Lee, Ting-I, Tsai, Wen-Chin, Chen, Shih-Ann, Chen, Yi-Jen
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper: Pathology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342473/
https://ncbi.nlm.nih.gov/pubmed/27713141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12470
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires