Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes

Fibroblast growth factor 23 (FGF23), elevated in chronic renal failure, increases atrial arrhythmogenesis and dysregulates calcium homeostasis. Late sodium currents (I(Na-Late)) critically induces ectopic activity of pulmoanry vein (the most important atrial fibrillation trigger). This study was to...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Huang, Shih-Yu, Chen, Yao-Chang, Kao, Yu-Hsun, Hsieh, Ming-Hsiung, Lin, Yung-Kuo, Chung, Cheng-Chih, Lee, Ting-I, Tsai, Wen-Chin, Chen, Shih-Ann, Chen, Yi-Jen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper: Pathology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342473/
https://ncbi.nlm.nih.gov/pubmed/27713141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12470
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