Redox and Activation of Protein Kinase A Dysregulates Calcium Homeostasis in Pulmonary Vein Cardiomyocytes of Chronic Kidney Disease

BACKGROUND: Chronic kidney disease (CKD) increases the occurrence of atrial fibrillation and pulmonary vein (PV) arrhythmogenesis. Calcium dysregulation and reactive oxygen species (ROS) enhance PV arrhythmogenic activity. The purposes of this study were to investigate whether CKD modulates PV elect...

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Bibliographic Details
Published in:J Am Heart Assoc
Main Authors: Huang, Shih‐Yu, Chen, Yao‐Chang, Kao, Yu‐Hsun, Hsieh, Ming‐Hsiung, Lin, Yung‐Kuo, Chen, Shih‐Ann, Chen, Yi‐Jen
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586294/
https://ncbi.nlm.nih.gov/pubmed/28701305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.005701
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