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Iron deficiency disrupts embryonic haematopoiesis but not the endothelial to haematopoietic transition

In this study, we aimed to explore how cellular iron status affects embryonic haematopoiesis. For this purpose, we used a model of mouse embryonic stem cell differentiation into embryonic haematopoietic progenitors. We modulated the iron status by adding either the iron chelator Deferoxamine (DFO) f...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Shvartsman, Maya, Bilican, Saygın, Lancrin, Christophe
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478831/
https://ncbi.nlm.nih.gov/pubmed/31015568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42765-y
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