Activation of the TGFβ pathway impairs endothelial to haematopoietic transition

The endothelial to haematopoietic transition (EHT) is a key developmental process where a drastic change of endothelial cell morphology leads to the formation of blood stem and progenitor cells during embryogenesis. As TGFβ signalling triggers a similar event during embryonic development called epit...

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Udgivet i:Sci Rep
Main Authors: Vargel, Özge, Zhang, Yang, Kosim, Kinga, Ganter, Kerstin, Foehr, Sophia, Mardenborough, Yannicka, Shvartsman, Maya, Enright, Anton J., Krijgsveld, Jeroen, Lancrin, Christophe
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759586/
https://ncbi.nlm.nih.gov/pubmed/26891705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21518
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