Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition

The endothelial to haematopoietic transition (EHT) is the process whereby haemogenic endothelium differentiates into haematopoietic stem and progenitor cells (HSPCs). The intermediary steps of this process are unclear, in particular the identity of endothelial cells that give rise to HSPCs is unknow...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Oatley, Morgan, Bölükbası, Özge Vargel, Svensson, Valentine, Shvartsman, Maya, Ganter, Kerstin, Zirngibl, Katharina, Pavlovich, Polina V., Milchevskaya, Vladislava, Foteva, Vladimira, Natarajan, Kedar N., Baying, Bianka, Benes, Vladimir, Patil, Kiran R., Teichmann, Sarah A., Lancrin, Christophe
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989687/
https://ncbi.nlm.nih.gov/pubmed/31996681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14171-5
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