Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition

The endothelial to haematopoietic transition (EHT) is the process whereby haemogenic endothelium differentiates into haematopoietic stem and progenitor cells (HSPCs). The intermediary steps of this process are unclear, in particular the identity of endothelial cells that give rise to HSPCs is unknow...

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Vydáno v:Nat Commun
Hlavní autoři: Oatley, Morgan, Bölükbası, Özge Vargel, Svensson, Valentine, Shvartsman, Maya, Ganter, Kerstin, Zirngibl, Katharina, Pavlovich, Polina V., Milchevskaya, Vladislava, Foteva, Vladimira, Natarajan, Kedar N., Baying, Bianka, Benes, Vladimir, Patil, Kiran R., Teichmann, Sarah A., Lancrin, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989687/
https://ncbi.nlm.nih.gov/pubmed/31996681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14171-5
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