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Glucocorticoid‐Induced Autophagy Protects Osteocytes Against Oxidative Stress Through Activation of MAPK/ERK Signaling

Autophagy confers protective or detrimental effects on cells depending on the cellular context. We showed here that oxidative stress‐induced cell death in osteocytic MLO‐Y4 cells coincided with decreased autophagy. Decreased autophagy was also observed in osteocytes of superoxide dismutase 1‐ (SOD1‐...

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Publicat a:JBMR Plus
Autors principals: Kar, Rekha, Riquelme, Manuel A., Hua, Rui, Jiang, Jean X.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478584/
https://ncbi.nlm.nih.gov/pubmed/31044179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10077
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