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Glucocorticoid‐Induced Autophagy Protects Osteocytes Against Oxidative Stress Through Activation of MAPK/ERK Signaling

Autophagy confers protective or detrimental effects on cells depending on the cellular context. We showed here that oxidative stress‐induced cell death in osteocytic MLO‐Y4 cells coincided with decreased autophagy. Decreased autophagy was also observed in osteocytes of superoxide dismutase 1‐ (SOD1‐...

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Detalhes bibliográficos
Publicado no:JBMR Plus
Main Authors: Kar, Rekha, Riquelme, Manuel A., Hua, Rui, Jiang, Jean X.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478584/
https://ncbi.nlm.nih.gov/pubmed/31044179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10077
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