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Elevated Intracellular Ca(2+) Signals by Oxidative Stress Activate Connexin 43 Hemichannels in Osteocytes
Elevated oxidative stress (OS) during aging leads to bone loss. OS increases intracellular Ca(2+) ([Ca(2+)](i)), resulting in cellular damage and death. We show earlier that Cx43 hemichannels open in response to OS, which serves as a protective mechanism for osteocytes. However, the underlying mecha...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Bone Res |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472115/ https://ncbi.nlm.nih.gov/pubmed/26273513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4248/BR201304006 |
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