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KCNQ1 rescues TMC1 plasma membrane expression but not mechanosensitive channel activity

Transmembrane channel-like protein isoform 1 (TMC1) is essential for generation of mechano-electrical transducer currents in hair cells of the inner ear. TMC1 disruption causes hair cell degeneration and deafness in mice and humans. Although thought to be expressed at the cell surface in vivo, TMC1...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Physiol
Egile Nagusiak: Harkcom, William T., Papanikolaou, Maria, Kanda, Vikram, Crump, Shawn M., Abbott, Geoffrey W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478532/
https://ncbi.nlm.nih.gov/pubmed/30613966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.28013
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