Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis

Diabetes mellitus is associated with various disorders of the locomotor system including the decline in mass and function of skeletal muscle. The mechanism underlying this association has remained ambiguous, however. We now show that the abundance of the transcription factor KLF15 as well as the exp...

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發表在:JCI Insight
Main Authors: Hirata, Yu, Nomura, Kazuhiro, Senga, Yoko, Okada, Yuko, Kobayashi, Kenta, Okamoto, Shiki, Minokoshi, Yasuhiko, Imamura, Michihiro, Takeda, Shin’ichi, Hosooka, Tetsuya, Ogawa, Wataru
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2019
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478420/
https://ncbi.nlm.nih.gov/pubmed/30830866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124952
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