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Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis

Diabetes mellitus is associated with various disorders of the locomotor system including the decline in mass and function of skeletal muscle. The mechanism underlying this association has remained ambiguous, however. We now show that the abundance of the transcription factor KLF15 as well as the exp...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Hirata, Yu, Nomura, Kazuhiro, Senga, Yoko, Okada, Yuko, Kobayashi, Kenta, Okamoto, Shiki, Minokoshi, Yasuhiko, Imamura, Michihiro, Takeda, Shin’ichi, Hosooka, Tetsuya, Ogawa, Wataru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478420/
https://ncbi.nlm.nih.gov/pubmed/30830866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124952
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