Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis

Diabetes mellitus is associated with various disorders of the locomotor system including the decline in mass and function of skeletal muscle. The mechanism underlying this association has remained ambiguous, however. We now show that the abundance of the transcription factor KLF15 as well as the exp...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Hirata, Yu, Nomura, Kazuhiro, Senga, Yoko, Okada, Yuko, Kobayashi, Kenta, Okamoto, Shiki, Minokoshi, Yasuhiko, Imamura, Michihiro, Takeda, Shin’ichi, Hosooka, Tetsuya, Ogawa, Wataru
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478420/
https://ncbi.nlm.nih.gov/pubmed/30830866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124952
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