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Thrombospondin 1 Suppresses Insulin Signaling in C2C12 Myotubes

Thrombospondin 1 (TSP-1) is abundantly expressed in visceral adipose tissue and this expression is up-regulated in obese humans and rodents. Recent studies showed that genetic deletion of TSP-1 protects mice from diet-induced insulin resistance. However, the molecular mechanism is largely unknown. I...

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Detalhes bibliográficos
Publicado no:Kobe J Med Sci
Main Authors: MATSUGI, KAKU, HOSOOKA, TETSUYA, NOMURA, KAZUHIRO, OGAWA, WATARU
Formato: Artigo
Idioma:Inglês
Publicado em: Kobe University School Of Medicine 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433728/
https://ncbi.nlm.nih.gov/pubmed/27492207
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