Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice

Previous studies have shown that proteasome inhibition can have beneficial effects in dystrophic mouse models. In this study, we have investigated the effects of a new selective proteasome inhibitor, CLi, a strong caspase-like inhibitor of the 20S proteasome, on skeletal and cardiac muscle functions...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Hovhannisyan, Yeranuhi, Melikyan, Gagik, Mougenot, Nathalie, Gao-Li, Jacqueline, Friguet, Bertrand, Paulin, Denise, Li, Zhenlin, Ferry, Arnaud, Agbulut, Onnik
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478376/
https://ncbi.nlm.nih.gov/pubmed/31013315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215821
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