Dicer regulates activation of the NLRP3 inflammasome

Inflammation plays a critical role in initiation of adaptive immunity, pathogen clearance and tissue repair. Interleukin (IL)-1β is a potent pro-inflammatory cytokine and therefore its production is tightly regulated: its secretion requires the assembly of a macromolecular protein complex, termed th...

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Udgivet i:PLoS One
Main Authors: Ojcius, David M., Jafari, Ardavan, Yeruva, Laxmi, Schindler, Christian W., Abdul-Sater, Ali A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478321/
https://ncbi.nlm.nih.gov/pubmed/31013297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215689
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