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Mechanism and regulation of NLRP3 inflammasome activation
Members of the nucleotide-binding domain and leucine-rich repeat containing (NLR) family and the pyrin and HIN-domain (PYHIN) family can form multiprotein complexes termed “inflammasomes”. The biochemical function of inflammasomes is to activate caspase-1, which leads to the maturation of interleuki...
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| Publicado no: | Trends Biochem Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123939/ https://ncbi.nlm.nih.gov/pubmed/27669650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.09.002 |
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