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Mechanism and regulation of NLRP3 inflammasome activation

Members of the nucleotide-binding domain and leucine-rich repeat containing (NLR) family and the pyrin and HIN-domain (PYHIN) family can form multiprotein complexes termed “inflammasomes”. The biochemical function of inflammasomes is to activate caspase-1, which leads to the maturation of interleuki...

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Bibliografski detalji
Izdano u:Trends Biochem Sci
Glavni autori: He, Yuan, Hara, Hideki, Núñez, Gabriel
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123939/
https://ncbi.nlm.nih.gov/pubmed/27669650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.09.002
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