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The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
The NLRP3 inflammasome is a critical component of the innate immune system that mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in response to microbial infection and cellular damage. However, the aberrant activation of the NLRP3 inflammasome has been linked...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6651423/ https://ncbi.nlm.nih.gov/pubmed/31284572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133328 |
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