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Drugging in the absence of p53

Inactivation of the p53 gene is a key driver of tumorigenesis in various cancer cohorts and types. The quest for a successful p53-based therapy that holds the promise of treating more than half of the cancer population has culminated in extensive knowledge about the role and function of p53 and led...

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Detalhes bibliográficos
Publicado no:J Mol Cell Biol
Main Authors: Aning, Obed Akwasi, Cheok, Chit Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478123/
https://ncbi.nlm.nih.gov/pubmed/30865230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz012
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