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p53-based Cancer Therapy

Inactivation of p53 functions is an almost universal feature of human cancer cells. This has spurred a tremendous effort to develop p53 based cancer therapies. Gene therapy using wild-type p53, delivered by adenovirus vectors, is now in widespread use in China. Other biologic approaches include the...

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Detalhes bibliográficos
Main Authors: Lane, David P., Cheok, Chit Fang, Lain, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926755/
https://ncbi.nlm.nih.gov/pubmed/20463003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001222
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