Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation

BACKGROUND: Alzheimer’s disease (AD) is responsible for 60–70% of all cases of dementia. On the other hand, the tap water consumed by hundreds of millions of people has been fluoridated to prevent tooth decay. However, little is known about the influence of fluoride on the expression of APP and subs...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Cao, Kun, Xiang, Jie, Dong, Yang-Ting, Xu, Yi, Li, Yi, Song, Hui, Zeng, Xiao-Xiao, Ran, Long-Yan, Hong, Wei, Guan, Zhi-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477877/
https://ncbi.nlm.nih.gov/pubmed/31010414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0490-3
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