Vaccine Development to Treat Alzheimer's Disease Neuropathology in APP/PS1 Transgenic Mice

A novel vaccine addressing the major hallmarks of Alzheimer's disease (AD), senile plaque-like deposits of amyloid beta-protein (Aβ), neurofibrillary tangle-like structures, and glial proinflammatory cytokines, has been developed. The present vaccine takes a new approach to circumvent failures...

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Detalhes bibliográficos
Main Authors: Carrera, Iván, Etcheverría, Ignacio, Fernández-Novoa, Lucía, Lombardi, Valter, Cacabelos, Ramón, Vigo, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457670/
https://ncbi.nlm.nih.gov/pubmed/23024882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/376138
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