Immunocytochemical Characterization of Alzheimer Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine

APP/PS1 double-transgenic mouse models of Alzheimer's disease (AD), which overexpress mutated forms of the gene for human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neuropathological hallmarks of AD-like pattern at early ages. This study characterizes immunocyt...

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Detalhes bibliográficos
Main Authors: Carrera, Iván, Etcheverría, Ignacio, Li, Yi, Fernández-Novoa, Lucía, Lombardi, Valter, Vigo, Carmen, Palacios, Hector H., Benberin, Valery V., Cacabelos, Ramón, Aliev, Gjumrakch
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782057/
https://ncbi.nlm.nih.gov/pubmed/24089686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/709145
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