HGG-04. USE OF AN ADVANCED RNA-SEQ FUSION PIPELINE RESULTS IN THE TARGETED TREATMENT AND SUSTAINED CLINICAL RESPONSE OF CHILDREN WITH RECURRENT PEDIATRIC HIGH-GRADE GLIOMA

BACKGROUND: Pediatric diffuse intrinsic pontine glioma (DIPG) and recurrent high-grade glioma (HGG) have an average progression-free survival (PFS) of 3 months. Gene fusions in cancer are being targeted with promising results. However, targeting fusions in DIPG and HGG has largely been unexplored –...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Schwark, Kallen, Bruzek, Amy, Kumar-Sinha, Chandan, Escolero, Sylvia, Marini, Bernard, Pasternak, Amy, Leonard, Marcia, Robertson, Patricia, Mody, Rajen, Chinnaiyan, Arul, Koschmann, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
High Grade Glioma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477381/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.098
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