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HGG-04. ZINC ENHANCES TEMOZOLOMIDE CYTOTOXICITY IN PEDIATRIC GLIOBLASTOMA MULTIFORME MODEL SYSTEM

BACKGROUND: Temozolomide (TMZ) is an alkylating agent that has become the mainstay treatment of the most malignant brain cancer, glioblastoma multiforme (GBM). Unfortunately only a limited number of patients respond to it positively. We have shown that zinc metal reestablishes chemosensitivity in ad...

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Publicado en:Neuro Oncol
Main Authors: Toren, Amos, Yalon, Michal, Dafni, Aner, Mehrian-Shai, Ruty
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715196/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.295
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