Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems

Temozolomide (TMZ) is an alkylating agent that has become the mainstay treatment of the most malignant brain cancer, glioblastoma multiforme (GBM). Unfortunately only a limited number of patients positively respond to it. It has been shown that zinc metal reestablishes chemosensitivity but this effe...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Toren, Amos, Pismenyuk, Tatyana, Yalon, Michal, Freedman, Shani, Simon, Amos J., Fisher, Tamar, Moshe, Itai, Reichardt, Juergen K.V., Constantini, Shlomi, Mardor, Yael, Last, David, Guez, David, Daniels, Dianne, Assoulin, Moria, Mehrian-Shai, Ruty
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342707/
https://ncbi.nlm.nih.gov/pubmed/27556862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11382
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