Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems

Temozolomide (TMZ) is an alkylating agent that has become the mainstay treatment of the most malignant brain cancer, glioblastoma multiforme (GBM). Unfortunately only a limited number of patients positively respond to it. It has been shown that zinc metal reestablishes chemosensitivity but this effe...

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Publicat a:Oncotarget
Autors principals: Toren, Amos, Pismenyuk, Tatyana, Yalon, Michal, Freedman, Shani, Simon, Amos J., Fisher, Tamar, Moshe, Itai, Reichardt, Juergen K.V., Constantini, Shlomi, Mardor, Yael, Last, David, Guez, David, Daniels, Dianne, Assoulin, Moria, Mehrian-Shai, Ruty
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342707/
https://ncbi.nlm.nih.gov/pubmed/27556862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11382
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