Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems

Temozolomide (TMZ) is an alkylating agent that has become the mainstay treatment of the most malignant brain cancer, glioblastoma multiforme (GBM). Unfortunately only a limited number of patients positively respond to it. It has been shown that zinc metal reestablishes chemosensitivity but this effe...

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Publicado en:Oncotarget
Main Authors: Toren, Amos, Pismenyuk, Tatyana, Yalon, Michal, Freedman, Shani, Simon, Amos J., Fisher, Tamar, Moshe, Itai, Reichardt, Juergen K.V., Constantini, Shlomi, Mardor, Yael, Last, David, Guez, David, Daniels, Dianne, Assoulin, Moria, Mehrian-Shai, Ruty
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342707/
https://ncbi.nlm.nih.gov/pubmed/27556862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11382
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