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ATRT-12. BINIMETINIB SUPPRESSES THE GROWTH OF ATYPICAL TERATOID/RHABDOID TUMOR CELLS AND INDUCES APOPOTOSIS
Atypical teratoid/rhabdoid (AT/RT) tumors are a class of malignant CNS tumors disproportionately affecting children with limited therapeutic options. Our group has previously demonstrated that the MAP kinase pathway is altered in a large proportion of these tumors and the MEK inhibitor selumetinib d...
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| 出版年: | Neuro Oncol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477334/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.011 |
| タグ: |
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