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ATRT-12. BINIMETINIB SUPPRESSES THE GROWTH OF ATYPICAL TERATOID/RHABDOID TUMOR CELLS AND INDUCES APOPOTOSIS
Atypical teratoid/rhabdoid (AT/RT) tumors are a class of malignant CNS tumors disproportionately affecting children with limited therapeutic options. Our group has previously demonstrated that the MAP kinase pathway is altered in a large proportion of these tumors and the MEK inhibitor selumetinib d...
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| Publicado en: | Neuro Oncol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477334/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.011 |
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