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LGG-11. ESTABLISHMENT OF A HUMAN 3-DIMENSIONAL LOW-GRADE GLIOMA TUMOR MODEL IN INDUCED PLURIPOTENT STEM CELL DERIVED BRAIN ORGANOIDS
INTRODUCTION: Low-grade glioma (LGG) are the most common pediatric brain tumors. Preclinical models are still scarce. We used human induced pluripotent stem cell (hiPSC) derived brain organoids for human LGG disease modeling. METHODS: Brain organoids were generated from hiPSC cells using the STEMdif...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477300/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.154 |
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