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DIPG-32. COMBINATION OF ChIP-SEQ AND RNA-SEQ ANALYSIS FOR TARGET DISCOVERY REVEAL PROMISING CANDIDATES FOR VALIDATION
INTRODUCTION: Diffuse intrinsic pontine glioma (DIPG) has one of the lowest overall survival amongst pediatric brain cancers. DIPG can be stratified into molecular subtypes dictated by histone mutational status: H3.3K27M, H3.1K27M, and H3 wildtype. Mutant histone proteins drive cellular proliferatio...
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| Publicado en: | Neuro Oncol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477283/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.053 |
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