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DIPG-32. COMBINATION OF ChIP-SEQ AND RNA-SEQ ANALYSIS FOR TARGET DISCOVERY REVEAL PROMISING CANDIDATES FOR VALIDATION

INTRODUCTION: Diffuse intrinsic pontine glioma (DIPG) has one of the lowest overall survival amongst pediatric brain cancers. DIPG can be stratified into molecular subtypes dictated by histone mutational status: H3.3K27M, H3.1K27M, and H3 wildtype. Mutant histone proteins drive cellular proliferatio...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Kim, Yong Yean, Andricovich, Jaclyn, Yadavilli, Sridevi, Kambhampati, Madhuri, Mueller, Sabine, Tzatsos, Alexandros, Nazarian, Javad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477283/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.053
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