DIPG-26. ACVR1 R206H COOPERATES WITH H3.1K27M IN PROMOTING DIFFUSE INTRINSIC PONTINE GLIOMA PATHOGENESIS

Diffuse intrinsic pontine glioma (DIPG) is an incurable pediatric brain tumor, resulting in the death of 200–300 children each year in the United States. Recently it was discovered that approximately 25% of all DIPG cases harbor activating ACVR1mutations, a gene that encodes Activin A receptor (ALK2...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hoeman, Christine, Cordero, Francisco, Hu, Guo, Misuraca, Katie, Romero, Megan, Cardona, Herminio, Nazarian, Javad, Hashizume, Rintaro, McLendon, Roger, Yu, Paul, Procissi, Daniele, Gadd, Samantha, Becher, Oren
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Diffuse Intrinsic Pontine Glioma (DIPG)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477246/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.047
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