IMMU-18. TARGETING H3.3 K27M MUTATION AS A SHARED NEOANTIGEN IN HLA-A*0201+ PATIENTS WITH DIFFUSE MIDLINE GLIOMAS – DEVELOPMENT OF A NOVEL MASS CYTOMETRY-BASED MONITORING OF VACCINE-REACTIVE, EPITOPE-SPECIFIC CD8+ T CELL RESPONSES

Diffuse midline glioma (DMG), including diffuse intrinsic pontine glioma (DIPG) constitutes up to 20% of pediatric brain cancer and has a median survival of less than one year. The ongoing development of immunotherapy has shown significant promise in many fields, including that of gliomas. Genetic s...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Taitt, Jared, Watchmaker, Payal, Almeida, Neil, Okada, Kaori, Shahin, Maryam, Mueller, Sabine, Okada, Hideho
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Immunology/Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477239/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.138
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