Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas()

BACKGROUND: Ependymomas (EPNs) are the third most common brain tumor in children. These tumors are resistant to available chemotherapeutic treatments, therefore new effective targeted therapeutics must be identified. Increasing evidence shows epigenetic alterations including histone posttranslationa...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Lewis, Rebecca, Li, Yuping D, Hoffman, Lindsey, Hashizume, Rintaro, Gravohac, Gordan, Rice, Gavin, Wadhwani, Nitin R, Jie, Chunfa, Pundy, Tatiana, Mania-Farnell, Barbara, Mayanil, Chandra S, Soares, Marcelo B, Lei, Ting, James, Charles D, Foreman, Nicolas K, Tomita, Tadanori, Xi, Guifa
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477190/
https://ncbi.nlm.nih.gov/pubmed/31005631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.03.012
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