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HGG-19. BONE MORPHOGENETIC PROTEIN 4 DIFFERENTIATES GLIOMA STEM CELLS TO INCREASES CHEMOSENSITIVITY VIA DECREASING H3K4me3 IN PEDIATRIC HIGH GRADE GLIOMAS

Glioma stem cells (GSCs), with neural stem cell (NSC) like properties are key factors behind therapeutic resistance in pediatric high-grade gliomas (HGG), the second most formidable childhood cancers. Targeting GSCs is a promising pathway for enhancing therapeutic effect and improving patient outcom...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Nayak, Sonali, Best, Benamin, Hayes, Emily, Mania-Farnell, Barbara, Tomita, Tadanori, Xi, Guifa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012222/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.291
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