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HGG-19. BONE MORPHOGENETIC PROTEIN 4 DIFFERENTIATES GLIOMA STEM CELLS TO INCREASES CHEMOSENSITIVITY VIA DECREASING H3K4me3 IN PEDIATRIC HIGH GRADE GLIOMAS
Glioma stem cells (GSCs), with neural stem cell (NSC) like properties are key factors behind therapeutic resistance in pediatric high-grade gliomas (HGG), the second most formidable childhood cancers. Targeting GSCs is a promising pathway for enhancing therapeutic effect and improving patient outcom...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012222/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.291 |
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